Tuberculosis tb, disproportionally affecting the worlds poorest populations, remains one of the biggest public health problems in the 21st century. Directly observed therapy training curriculum for tb control programs. Ppt pulmonary tuberculosis powerpoint presentation. Thus, drug resistance in tuberculosis is a manmade problem. Ppt anti mycobacterial drugs powerpoint presentation. Nov 12, 2015 mar 19, 2020 treatment of tuberculosis pptpowerpoint presentation, medical notes edurev is made by best teachers of. Anybody with symptoms suggestive of tb should be investigated. It must be given in combination with other antituberculosis drugs. The adobe flash plugin is needed to view this content. Multidrugresistant tb mdrtb is multifactorial and fuelled by improper treatment of patients, poor management of supply and quality of drugs, and airborne transmission of bacteria in public. Despite the complexities of simultaneously treating two infections requiring multidrug therapy, antiretroviral therapy is lifesaving among patients with tuberculosis. Anti tb drugs free download as powerpoint presentation. Overview of tuberculosis epidemiology, transmission.
Reported tb cases united states, 19822011 ses year cdc. Isoniazid mechanism the activated form of isoniazid forms a covalent complex with an inha acyl carrier protein acpm and kasa, a. Tuberculosis pericarditis the pericardium is affected in this condition causing the space between the pericardium and the heart to fill with fluid, impeding the hearts ability to fill with blood and beat efficiently. Who, therefore has recommended dotsdirectly observed therapy for short course wherein the antitb drugs are given under direct supervision of medical professional 3 days a week.
Handbook of anti tuberculosis agents global alliance for tb drug development 80 broad street new york, ny 4, usa. Anti tuberculosis drug resistance in the world report no. Join our community just now to flow with the file tuberculosis and make our shared file collection even more complete and exciting. When someone comes into contact with tuberculosis or feels as if they become infected by tuberculosis, they should call a doctor and order a skin test. Disease is most common in south east asia, sub saharan region, eastern. Ppt pulmonary tuberculosis powerpoint presentation free. Among the 4 standard antitb drugs, isoniazid inh is the. Treatment of tuberculosis pptpowerpoint presentation.
Introductionintroductionpulmonary tuberculosis tb is an infectiouspulmonary tuberculosis tb is an. Ppt antituberculosis drugs powerpoint presentation, free. Obligate aerobe and a very slow grower growth on solid culture takes 38 weeks typically neutral on grams staining, however, once stained, the bacilli cannot be decolorized by acid alcohol. Co1 pretomanid and bpal regimen for treatment of highlyresistant tuberculosis june 6, 2019 tb alliance antimicrobial drugs advisory committee. The anti tuberculosis activity of the combination of moxifloxacin, pretomanid pa824 and pyrazinamide during the first eight weeks. Fdcs are recommended as they have many advantages in improving adherence, removing the risk of patients taking only part of the prescribed medications, reducing the risk of failure and development of resistance. Her excellency the marchioness of linlithgow was the first president of the association when the tuberculosis association of india was established on february 23, 1939. Tuberculosis management refers to the medical treatment of the infectious disease tuberculosis tb the standard short course treatment for tb is isoniazid along with pyridoxal phosphate to obviate peripheral neuropathy caused by isoniazid, rifampicin also known as rifampin in the united states, pyrazinamide, and ethambutol for two months, then isoniazid and rifampicin alone for a. Free tuberculosis types medical powerpoint template for. Ppt antituberculosis drugs powerpoint presentation.
Hepatotoxicity acetyl hydrazine cause the damage in serum transaminase clinical hepatitis can be fatal if not withdrawn promptly peripheral neuropathy parasthesia,numbness due to relative def. Information on treatment for tb disease, including regimens for drugsusceptible tb. Up to a decade ago only 10 percent of total tuberculosis patients suffered from genital tuberculosis, but the percentage has now increased to 30 percent due to lack of awareness. Department of health and human services, cdc, october 2012. Anti tuberculosis agents free download as powerpoint presentation. Introductionintroductionpulmonary tuberculosis tb is an infectiouspulmonary tuberculosis. Uninterrupted supply of quality assured secondline anti tuberculosis drugs.
Tuberculosis tb is a disease that has affected mankind for centuries and dates as far back as ancient egyptian times. The disease is spread by coughing, talking, spitting or sneezing which. Resistance to tuberculosis tb drugs is a formidable obstacle to effective tb care and prevention globally. All firstline anti tuberculous drug names have a standard threeletter and a singleletter. The designations employed and the presentation of material in this health information product. Provided by the centers for disease control and prevention cdc. Female genital tuberculosis causes, treatment, tests doc n me. Managing drug interactions in the treatment of hivrelated. The ideal number of drugs needed and treatment duration are crucial issues in the management of multidrugresistant tuberculosis mdrtb. Anti tuberculosis tuberculosis medicinal chemistry.
Nov 12, 2014 treatment of tuberculosis one of the main reason for threrapeutic failure has been patients poor compliancen after having symptomatic relief. Treatment of tuberculosis one of the main reason for threrapeutic failure has been patients poor compliancen after having symptomatic relief. Genital tuberculosis is increasing in incidence among women. Appropriate treatment strategies that utilize second line drugs. Describe tuberculosis tb disease treatment adherence strategies identify antitb drugs describe treatment regimens for tb disease describe patient. The treatment of mdrxdrtb is unfortunately long, toxic and expensive, and the success rate largely unsatisfactory download fulltext pdf. Scribd is the worlds largest social reading and publishing site. Jun 22, 2014 extensively drugresistant tb xdrtb is a form of tb caused by organisms that are resistant to isoniazid and rifampicin i. Adverse effects dose related and duration dependent loss of visual acuityred green colour vision optic neuritisfield defects should not be used in children less than 6y nausea, rashes, fever, hyperuricemia, neurological changesheadache, dizziness, mental confusion, hallucination, numbness, tingling of fingers. Download ppt the authors then carried out a set of detailed analyses of rv0222 also known as echa1 to show that it plays an important role in m. Who surveillance of drug resistance in tuberculosis. Classification according to clinical utility the anti tb drugs can be divided into 2 groups first line. Management of common sign effects of inh final draft. Tuberculosis airborne disease caused by the bacterium mycobacterium tuberculosis m.
The emergence of multi drug resistant tuberculosis mdrtb is of concern to both patients and clinicians because of the attendant increased mortality and morbidity. Update on anti tubercular drugs authorstream presentation. A free powerpoint ppt presentation displayed as a flash slide show on id. Appropriate treatment strategies that utilize second line drugs under proper management conditions. Microsoft powerpoint tb epidemiology, etiopathogenesis and cilinical picture lecture 5th year re\236im kompatibility. Thus, we read with interest the article by the collaborative group for the metaanalysis of individual patient data in mdrtb treatment2017,1 the results of which support our proposal,2 from 2015, to classify anti tuberculosis drugs on the basis of. Dec 08, 20 recommended doses of firstline antituberculosis drugs for adults 6. Apr 16, 2019 there are some unique challenges in the management of tuberculosis in these patients, including an increased risk of death, failure of anti tuberculosis treatment, and recurrent disease once treatment is complete. Objectives the objective of this study was to investigate the association between genetic polymorphisms of nacetyltransferase 2 nat2, cytochrome p450 2e1 cyp2e1, glutathione stransferase gst and solute carrier organic anion transporter family member 1b1 slco1b1 and the risk of anti tuberculosis druginduced liver injury atdili. A brief overview of current firstline and recent drugs such as fluoroquinolones. Anti tuberculosis agents medical treatments pharmacology. Additionally, patients with diabetes might present atypically with tuberculosis, making diagnosis more difficult. With the emerging dilemma of multidrug resistant tuberculosis mdrtb and. Citescore values are based on citation counts in a given year e.
This medical powerpoint template will fit presentations on medical tests, tuberculosis disease, distribution of tuberculosis, tuberculin tests, pulmonary tb, tubercle bacillus, etc. Deepak k gupta slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Anti tuberculosis medicinal chemistry pharmacology. Pulmonary tuberculosis powerpoint presentation free to download id.
Osteal tuberculosis infection of any bone can occur, but one of the most common sites is the spine. Tuberculosis remains the worlds leading cause of death from an infectious disease, responsible for an estimated 1 674 000 deaths annually. The disease is spread by coughing, talking, spitting or sneezing which slideshow 2176860. The hallmark of childhood pulmonary tuberculosis is the relatively large size and importance of the hilar lymphadenitis compared with the less significant size of.
This free tuberculosis types medical ppt is one of the free medical powerpoint templates available for medical and healthcare professionals on. Recommended doses of firstline anti tuberculosis drugs for adults 6. Pretomanid and bpal regimen for treatment of highlyresistant. This report provides an analysis of drug resistance survey and surveillance data from 77 different countriesgeographical settings, between 1999 and 2002 by who and the international union against tuberculosis and lung disease global project. Fdc in presence of other firstline antituberculosis drugs. Introduction drug resistant tuberculosis especially multi drug resistant mdr tuberculosis and extensive drug resistant xdr tb is a. You are get attractive tuberculosis powerpoint ppt templates for a good powerpoint template. Several important recommendations are being promoted in this new edition. Standard treatment regimens treatment of tuberculosis. Anti tuberculosis free download as powerpoint presentation. Fdcs are recommended as they have many advantages in improving adherence, removing the risk of patients taking. Jan 11, 2017 female genital tuberculosis is fast emerging as a major health issue that affects fertility levels in women.
Mar 11, 2020 download ppt the authors then carried out a set of detailed analyses of rv0222 also known as echa1 to show that it plays an important role in m. Association of genetic polymorphisms of cyp2e1, nat2, gst. Anti tubercular drugs 1 free download as powerpoint presentation. Ppt anti mycobacterial drugs powerpoint presentation free to download id. Over 480 000 cases of multidrugresistant mdr tuberculosis tb occur every year globally, 9% of them being affected by extensively drugresistant xdr strains of mycobacterium tuberculosis. Download figure open in new tab download powerpoint. First, the recommendation to discontinue the regimen based on just 2 months of rifampicin 2hrze6he and change to the regimen based on a full 6 months of. Tuberculosis tb is a symbolic menace to mankind, infecting almost one third of the worlds populace and causing over a million mortalities annually. Tuberculosis is a disease caused by a bacterium called mycobacterium tuberculosis which usually attack the lungs, but can attack any part of the body such as the kidney, spine, and brain.
Who, therefore has recommended dotsdirectly observed therapy for short course wherein the anti tb drugs are given under direct supervision of medical professional 3 days a week. If you continue browsing the site, you agree to the use of cookies on this website. Use the above tuberculosis owerpoint ppt template to make powerpoint template on tuberculosis. India is the country with the highest burden of tb, with world health organisation who statistics for 20 giving an estimated incidence of 2. Tuberculosis 2008 882 8586 introduction tuberculosis tb, disproportionally affecting the worlds poorest populations, remains one of the biggest public health problems in the 21st century. For many tb drugs, the administered dose is not predictive of the drug exposure and clinical effect. Multi drug resistant tuberculosis mdrtb is tuberculosis that is resistant to at least the first line anti tb drugs, rifampicin and isoniazid. Tuberculosis is completely curable disease now a days but one should follow the treatment regimens correctly. Figures are based on the most recent year for which data have been reported, which varies among countries. A question and answer session, a printable powerpoint slide file, and other useful. Tuberculosis powerpoint templates tuberculosis powerpoint. This tuberculosis powerpoint ppt template is designed for effective tuberculosis powerpoint slides with a colorful powerpoint background and theme. Mar 19, 2020 treatment of tuberculosis pptpowerpoint presentation, medical notes edurev is made by best teachers of. Management of tuberculosis anti tb medications if treating a patient with suspected mdrtb.
Who estimated 600 000 cases of rifampicinresistant tuberculosis in 2016of which 490 000 were multidrug resistant mdr, with less than 50% survival after receiving recommended treatment regimens. Distribution of tuberculosis tb is present worldwide the largest numbers of cases occur in the regions of southeast asia and subsaharan africa, reaching 700 cases per 100,000 individuals in some areas. Recording and reporting system designed for dotsplus programs. Describe tuberculosis tb disease treatment adherence strategies identify anti tb drugs describe treatment regimens for tb disease describe patient.
This slide presentation with streaming audio provides information on how to. Plasma concentrations of secondline antituberculosis drugs in. Dot is the preferred core management strategy recommended by cdc for treatment of tb disease and, if resources allow, for latent tuberculosis infection ltbi treatment. This document is highly rated by students and has been viewed 676 times. Mycobacterium tuberculosis mtb is the key pathogen of tb that invades and replicates inside the hosts macrophage. Tb prevention, diagnosis and treatment world health organization. Design and syntheses of antituberculosis agents inspired. Antituberculosis drug resistance in the world report no. The spread of multidrugresistant tb mdrtb and the appearance of extensively drugresistant tb xdrtb pose new challenges for the prevention. The current antitb drug research and development pipeline.
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